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Senior Scientist, iPSC Manager/Core Lead (Berkeley)
Senior Scientist, iPSC Manager/Core Lead (Berkeley)EPM Scientific • Berkeley, CA, United States
Senior Scientist, iPSC Manager / Core Lead (Berkeley)

Senior Scientist, iPSC Manager / Core Lead (Berkeley)

EPM Scientific • Berkeley, CA, United States
2 days ago
Job type
  • Full-time
Job description

The company is looking for a highly motivated, independent, and detail-oriented scientist to lead and expand our induced pluripotent stem cell (iPSC) core. This role is pivotal in establishing the foundation for preclinical research and future manufacturing readiness.

This is a high-impact position that begins with hands-on laboratory work-mastering systems, protocols, and team dynamics- and evolves into managing a large-scale iPSC platform encompassing multiple cell lines and differentiation pathways. You will implement robust quality control (QC) standards, ensure operational consistency, and develop scalable systems for long-term success.

Over time, you will broaden the core's capabilities to include predictive QC tools (e.g., imaging, sequencing), support translational workflows, and prepare for clinical-grade operations.

Key Responsibilities

Core Operations

  • Oversee daily operations of the iPSC core.
  • Maintain cell banks and perform QC on iPSCs and feeder lines.
  • Track QC data, reagents, consumables, and equipment; coordinate with Operations for facility upkeep.
  • Develop and maintain SOPs for routine workflows.
  • Collaborate with cell engineering teams to validate, QC, and integrate new cell lines.

Team Leadership

  • Mentor and manage a small team; set clear expectations for documentation and accountability.
  • Foster engagement and professional growth among junior scientists.
  • Communicate timelines, risks, and mitigation strategies across R&D and Operations.
  • Innovation & QC Development

  • Work with R&D teams to standardize and scale differentiation protocols for multiple lineages.
  • Partner with computational biology experts to implement predictive QC methods using imaging and RNA sequencing.
  • Propose and develop improvements to enhance cell quality, efficiency, and early risk detection.
  • Qualifications

  • PhD in Cell Biology, Developmental Biology, or related discipline (preferred), or Master's with significant industry experience.
  • Deep expertise in iPSC culture and differentiation to one or more lineages.
  • Proven ability to manage organized, traceable, and high-quality cell culture operations.
  • Experience mentoring or managing junior scientists.
  • Highly organized, detail-oriented, and proactive.
  • Strong communication and collaboration skills.
  • Drive to build scalable systems from research through preclinical readiness.
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